Lymphoma

Hodgkin
Non-Hodgkin
Path
·       B-Cell Lymphoma
·       Associated w/ EBV
·       B-Cell Lymphoma
S/S
·       LN
·       Constitutional Sx (caused by cytokines from RS cells)
·       They can have SVC syndrome
·       LN
·       Constitutional Sx
Types
·       Nodular Sclerosing 
·       most common
·       👩🏻 predominance
·       lymphocyte-rich
·       especially in < 35 yo
·       lymphocyte-depleted
·       especially in > 60
·       diffuse B-cell lymphoma
·       Burkitt lymphoma
·       follicular lymphoma
·       marginal zone lymphoma
·       mantle cell lymphoma
Dx
·       LN Bx
·       Reed-sternberg cells
·       CD 15 – 30
·       Imaging for staging
·       LN Bx
·       CD 20
Tx
·       Local: excision
·       Anyone w/ Constitutional Sx | Late stage:
·       ABVD Regimen
·       Adriamycin (doxorubicin)
·       Bleomycin
·       Vinblastine
·       Dacarbazin
CHOP:
·       Cyclophosphamide
·       Hydroxydaunorubicin
·       Vincristine
·       Prednisone

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