RF

·       Smoking

·       Rx pancreatitis for whatever reason

·       Obesity and lack of physical activity

S/S

·       Weight loss

·       Abdominal pain (tenderness)

·       Jaundice (if obstructive)

·       Recent dx of atypical DM

·       Migratory superficial thrombophlebitis

·       Hepatomegaly and ascites (mets)

Dx

·       Cholestasis (↑ ALP and direct bilirubin)

·       ↑Cancer-associated antigen 19-9

·       Abdominal ultrasound (if jaundiced) or CT scan (if no jaundice)