Rashes & Allergy

All of them –> Dx: clx / Tx: supportive
Learn to ddx b/w them, and thats it 😂
Neonatal rashes
Dx
S/S
Tx
Erythema Toxicum Neonatrum
·       Asymptomatic
·        Scattered, erythematous papules & pustules
None
Neonatal HSV
·       Three types:
·       Vesicular clusters on skin, eyes & mucous
·       membranes
·       CNS infection
·       Fulminant, disseminated, multiorgan disease
Acyclovir
Staphylococcal scalded skin syndrome
·       Fever, irritability
·       Diffuse erythema —+ flaccid, flexural blistering
·       +ve Nikolsky sign
Oxacillin, nafcillin, or
vancomycin
Measles (rubeola)
MOT
·       Airborne
Clx
·       Prodrome – 4 Cs (Cough, Coryza, Conjunctivitis, Koplik spots)
·       Maculopapular exanthem
    – Head -9 Body Spread
    – Spares palms/soles
PPx
·       Live-attenuated measles vaccine
Tx
·       Supportive
·       Vitamin A for hospitalized pt
Roseola infantum
👾
HHV-6 most common
#
Age <2 years  
Clx
3-5 days of high fever followed by
blanching maculopapular rash
Tx
 Supportive
Perianal (Ass) skin rashes
Contact dermatitis
Candida
Perianal Streptococcus
#
Most common cause in infants
Second most common cause in infants
School-aged children
PEx
Spares creases/skinfolds
Beefy-red rash involving
skinfolds with satellite lesions
Bright, sharply demarcated
erythema over
perianal/perineal area
Tx
Topical barrier ointment or
paste
Topical antifungal therapy
ORAL antibiotics
Infectious complications of Atopic Dermatitis
Dx
👾
Clx
Impetigo
Staphylococcus aureus
Streptococcus pyogenes
Painful, non-pruritic pustules with
honey-crusted adherent coating
Eczema herpeticum
Herpes simplex type I
Painful vesicular rash with “punched-out”
erosions & hemorrhagic crusting
Molluscum contagiosum
Poxvirus
Flesh-colored papules with central
umbilication
Tinea corporis
Trichophyton rubrum
Pruritic circular patch with central
clearing & raised, scaly border
 Nonbullous impetigo
👾
·       Staphylococcus aureus
·       Group A beta-hemolytic Streptococcus (S pyogenes)
Clx
·       Painful non-itchy pustules & honey-crusted lesions
Tx
·       Topical antibiotics (eg, mupirocin)
Complications
·       Poststreptococcal glomerulonephritis
Herpangina vs herpetic gingivostomatitis
Herpangina
Herpetic gingivostomatitis
Pathogen
Coxsackie A virus
HSV 1
Age
1-7 years
6 months-5 years
Timing
اخر الصيف – اول الخريف
يأتي في اي وقت
Clx
• Fever
• Pharyngitis
Gray vesicles/ulcers on oropharynx not  on lips
• Fever
• Pharyngitis
Erythematous gingiva
• Clusters of vesicles on oral mucosa/lips
Tx
Supportive
Oral acyclovir
Allergies
Anaphlaxis
Urticaria
Angioedema
HYPOTENSION
Rash
Wheezing
No hypotension
Only rash after exposure to allergen
No hypotension
Swelling (can be anywhere, but be careful for swelling around AW)
Dx: clx
Tx: Epi pen
Tx:
H1 Blocker
Steroids
Dx: Clx
Tx: Secure AW
 Anaphylaxis
?
·       Food (Nuts, shellfish)
·       Drugs (eg. ß-lactam antibiotics)
·       Insect stings
Clx
CVS
·       Vasodilation hypotension & tissue edema
RESP
·       Upper AW edema -9 stridor & hoarseness
·       Bronchospasm wheezing
SKIN
·       Urticarial rash, pruritus, flushing
Tx
·       IM epinephrine (Rz if no improvement)
·       AW management & volume resuscitation
·       Adjunctive therapy (Antihistamines, GCS)
Allergic rhinitis:
·       Sx: Shiner, pale boggy mucosa, cobblestoning
·       How to dx? Clx
·       Do I need to do any other tests (skin test)? No, except if the pt is refractory or you wanna desensetize
·       Tx: avoid triggers – Intranasal steroids.
Allergic conjunctivitis
Same as above. ⤴️
Same tx, H2>H1.
Food Allergies
·       Make sure there’s no anaphylaxis, if there’s –> make them have Epi pen
·       If they wanna know what type of food they are allergic to, just try all food u can get
·       Soy milk allergy is a lil bit frightening (it can present w/ bloody diarrhea or FTT) –> just change the formula
 Allergic Rhinitis
Sx
·       Rhinorrhea, congestion, sneezing, itching
·       Cough 2° to postnasal drip
·       Ocular itching & tearing
PEx
·       “Allergic shiners” (infraorbital edema & darkening)
·       “Allergic salute” (transverse nasal crease)
·       Pale, bluish, enlarged turbinates
·       Pharyngeal cobblestoning
·       “Allergic facies” (high-arched palate, open-mouth breathing)
Tx
·       Allergen avoidance
·       Intranasal corticosteroids

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