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PPD/TST
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Tx if:
|
|
≥5
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· HIV / immunosuppressed
· Recent contacts of known TB case
|
|
≥ 10 mm
|
· Immigrants
· IV drug users
· Residents & employees Of high-risk settings (eg, prisons, nursing homes, hospitals, homeless
· shelters)
· Mycobacteriology laboratory personnel
· Higher risk for TB reactivation (eg, DM, leukemia, ESRD, chronic malabsorption syndromes)
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|
≥ 15 mm
|
All Of the above plus healthy individuals
|
|
Isoniazid (INH) SE:
|
|
Severe INH hepatitis and a much milder hepatotoxicity.
|
|
How does SEVERE hepatitis presents? What to do about it?
Isoniazid hepatitis presents with clinical manifestations that are similar to those seen with viral hepatitis.
If signs and symptoms of INH hepatitis are observed, the drug should be discontinued immediately.
|
|
What’s subclinical hepatic injury?
mild, subclinical hepatic injury demonstrated only by minor elevations in serum aminotransferases (typically < 100 IU/L).
|
Fast HY Review 